Wellcome Book Prize Shortlist Event
Five of the six shortlisted authors (barring Dublin-based Mark O’Connell) were at the Wellcome Collection in London yesterday to share more about their books in mini-interviews with Lisa O’Kelly, the associate editor of the Observer. She called each author up onto the stage in turn for a five-minute chat about her work, and then brought them all up for a general conversation and audience questions. Clare and I found it a very interesting afternoon. Here’s some context that I gleaned about the five books and their writers.
Ayobami Adebayo says sickle cell anemia is a massive public health problem in Nigeria, as brought home to her when some friends died of complications of sickle cell. She herself was tested for the gene and learned that she is a carrier, so her children would have a 25% chance of having the disease if her partner was also a carrier. Although life expectancy with the disease has improved to 45–50, a cure is still out of reach for most Nigerians because bone marrow/stem cell transplantation and anti-rejection drugs are so expensive. Compared to the 1980s, when her book opens, she believes polygamy is becoming less fashionable in Nigeria and people are becoming more open to other means of becoming parents, whether IVF or adoption. It’s a way of acknowledging, she says, that parenthood is “not just about biology.”
Sigrid Rausing started writing her book soon after her sister-in-law Eva’s body was found: just random paragraphs to make sense of what had happened. From there it became an investigation, a quest to find the nature of addiction. She thinks that as a society we still don’t quite understand what addiction is, and the medical research and public perception are very separate. In addition to nature and nurture, she thinks we should consider the influence of culture – as an anthropologist by training, she’s very interested in drug culture and how that drew in her brother, Hans. Although there have been many memoirs by ex-addicts, she can’t think of another one by a family member. Perhaps, she suggested, this is because the addict is seen as the ultimate victim. She referred to her book as a “collage,” a very apt description.
Kathryn Mannix spoke of how her grandmother, born in 1900, saw so much more death than we do nowadays: siblings, a child, and so on. Today, though, Mannix has encountered people in their sixties who are facing, with their parents, their very first deaths. Death is fairly “gentle” and “dull” if you’re not directly involved, she insists; she blames Hollywood and Eastenders for showing unusually dramatic deaths. She said once you understand what exactly people are afraid of about dying (e.g. hell, oblivion, pain, leaving their families behind) you can address their specific concerns and thereby “beat out the demon of terror and fear.” Mannix never intended to write a book, but someone heard her on the radio and invited her to do so. Luckily, from her medical school days onward, she’d been writing an A4 page about each of her most mind-boggling cases to get them out of her head and move on. That’s why, as O’Kelly put it, the characters in her 30 stories “leap off the page.”

Mannix, Adebayo, O’Kelly, Rausing, Wadman & Fitzharris
Lindsey Fitzharris called The Butchering Art “a love story between science and medicine” – it was the first time that the former (antisepsis) was applied to the latter. She initially thought Robert Liston was her man – he was so colorful, larger than life – but eventually found that the real story was with Joseph Lister, the quiet, persistent Quaker. (However, the book does open with Liston performing the first surgery under ether.) Fitzharris is also involved in the Order of the Good Death, author Caitlin Doughty’s initiative, and affirmed Mannix’s efforts to remove the taboo from talking about death. I think I heard correctly that she said there is a film of The Butchering Art in the works?! I’ll need to look into that some more.
Meredith Wadman started with a brief explanation of how immunization works and why the 1960s were ripe for vaccine research. This segment went really science-y, which I thought was a little unfortunate as it may have made listeners tune out and be less interested in her work than the others’. It was perhaps inevitable given her subject matter, but also a matter of the questions O’Kelly asked – with the others she focused more on stories and themes than on scientific facts. It was interesting to hear what Wadman has been working on recently: for the past 6–8 months, she’s been reporting for Science on sexual harassment in science. For her next book, though, she’s pondering the conflict between a congressman and a Centers for Disease Control scientist over funding into research that might lead to gun control.
The question time brought up the issues of medical misinformation online, the distrust people with chronic illnesses have of medical professionals, and euthanasia – Mannix rather dodged that one, stating that her book is about the natural dying process so that’s not really her area. (Though it does come up in a chapter of her book.) We also heard a bit about the projects up next for each author. Rausing’s next book will be a travel memoir about the Capetown drought, taking in apartheid and her husband’s family’s immigration. Adebayo is at work on a very nebulous novel “about people,” and possibly how privilege affects access to healthcare.
Wellcome Book Prize Shadow Panel Decision
Addiction, death, infertility, surgery, transhumanism and vaccines: It’s been quite the varied reading list for the five of us this spring! Lots of science, lots of medicine, but also a lot of stories and imagination.
After some conferring and voting, we have arrived at our shadow panel winner for the Wellcome Book Prize 2018: To Be a Machine by Mark O’Connell.

Rarely have I been so surprised to love a book. It’s a delight to read, and no matter what your background or beliefs are, it will give you plenty to think about. It goes deep down, beneath our health and ultimately our mortality, to ask what the essence of being human is.
Here’s what the rest of the shadow panel has to say about our pick:
Annabel: “O’Connell, as a journalist and outsider in the surprisingly diverse field of transhumanism, treats everyone with respect: asking the questions, but not judging, to get to the heart of the transhumanists’ beliefs. For a subject based in technology, To Be a Machine is a profoundly human story.”
Clare: “The concept of transhumanism may not be widely known or understood yet, but O’Connell’s engaging and fascinating book explains the significance of the movement and its possible implications both in the distant future and how we live now.”
Laura: “My brain feels like it’s been wired slightly differently since reading To Be a Machine. It’s not just about weird science and weird scientists, but how we come to terms with the fact that even the luckiest of us live lives that are so brief.”
Paul: “An interesting book that hopefully will provoke further discussion as we embrace technology and it envelops us.”

On Monday we’ll find out which book the official judges have chosen. I could see three or four of these as potential winners, so it’s very hard to say who will take home the £30,000.
Who are you rooting for?
Wellcome Book Prize Blog Tour: Sigrid Rausing’s Mayhem
“Now that it’s all over I find myself thinking about family history and family memories; the stories that hold a family together and the acts that can split it apart.”
Sigrid Rausing’s brother, Hans, and his wife, Eva, were wealthy philanthropists – and drug addicts who kept it together long enough to marry and have children before relapsing. Hans survived that decade-long dive back into addiction, but Eva did not: in July 2012 the 48-year-old’s decomposed body was found in a sealed-off area of the couple’s £70 million Chelsea mansion. The postmortem revealed that she had been using cocaine, which threw her already damaged heart into a chaotic rhythm. She’d been dead in their drug den for over two months.
Those are the bare facts. Scandalous enough for you? But Mayhem is no true crime tell-all. It does incorporate the straightforward information that is in the public record – headlines, statements and appearances – but blends them into a fragmentary, dreamlike family memoir that proceeds through free association and obsessively deliberates about the nature and nurture aspects of addictive personalities. “We didn’t understand that every addiction case is the same dismal story,” she writes, in a reversal of Tolstoy’s maxim about unhappy families.

Rausing’s memories of idyllic childhood summers in Sweden reminded me of Tove Jansson stories, and the incessant self-questioning of a family member wracked by remorse is similar to what I’ve encountered in memoirs and novels about suicide in the family, such as Jill Bialosky’s History of a Suicide and Miriam Toews’ All My Puny Sorrows. Despite all the pleading letters and e-mails she sent Hans and Eva, and all the interventions and rehab spells she helped arrange, Rausing has a nagging “sense that when I tried I didn’t try hard enough.”
The book moves sinuously between past and present, before and after, fact and supposition. There are a lot of peculiar details and connections in this story, starting with the family history of dementia and alcoholism. Rausing’s grandfather founded the Tetra Pak packaging company, later run by her father. Eva had a pet conspiracy theory that her father-in-law murdered Swedish Prime Minister Olof Palme in 1986.
Rausing did anthropology fieldwork in Estonia and is now the publisher of Granta Books and Granta magazine. True to her career in editing, she’s treated this book project like a wild saga that had to be tamed, “all the sad and sordid details redacted,” but “I fear I have redacted too much,” she admits towards the end. She’s constantly pushing back against the more sensational aspects of this story, seeking instead to ground it in family experience. The book’s sketchy nature is in a sense necessary because information about her four nieces and nephews, of whom she took custody in 2007, cannot legally be revealed. But if she’d waited until they were all of age, might this have been a rather different memoir?
Mayhem effectively conveys the regret and guilt that plague families of addicts. It invites you to feel what it is really like to live through the “years of failed hope” that characterize this type of family tragedy. It doesn’t offer any easy lessons seen in hindsight. That makes it an uncomfortable read, but an honest one.
With thanks to Midas PR for the free copy for review.
My gut feeling: This book’s style could put off more readers than it attracts. I can think of two other memoirs from the longlist that I would have preferred to see in this spot. I suppose I see why the judges rate Mayhem so highly – Edmund de Waal, the chair of this year’s judging panel, describes the Wellcome shortlist as “books that start debates or deepen them, that move us profoundly, surprise and delight and perplex us” – but it’s not in my top tier.
See what the rest of the shadow panel has to say about this book:
Annabel’s review: “Rausing is clearly a perceptive writer. She is very hard on herself; she is brutally honest, knowing that others will be hurt by the book.”
Clare’s review: “Rausing writes thoughtfully about the nature of addiction and its many contradictions.”
Laura’s review: “One of the saddest bits of Mayhem is when Rausing simply lists some of the press headlines that deal with her family story in reverse order, illustrating the seemingly inescapable spiral of addiction.”
Paul’s review: “It is not an easy read subject wise, thankfully Rausing’s sparse but beautiful writing helps makes this an essential read.”
Also, be sure to visit Laura’s blog today for an exclusive extract from Mayhem.
Shortlist strategy: Tomorrow I’ll post a quick response to Meredith Wadman’s The Vaccine Race.
If you are within striking distance of London, please consider coming to one of the shortlist events being held this Saturday and Sunday.
I was delighted to be asked to participate in the Wellcome Book Prize blog tour. See below for details of where other reviews and extracts have appeared or will be appearing soon.

My Favorite Nonfiction Reads of 2015
Without further ado, I present to you my 15 favorite non-fiction books read in 2015. I’m a memoir junkie so many of these fit under that broad heading, but I’ve dipped into other areas too. I give two favorites for each category, then count down my top 7 memoirs read this year.
Note: Only four of these were actually published in 2015; for the rest I’ve given the publication year. Many of them I’ve already previewed through the year, so – like I did yesterday for fiction – I’m limiting myself to two sentences per title: the first is a potted summary; the second tells you why you should read this book. (Links given to full reviews.)
Foodie Lit
A Homemade Life: Stories and Recipes from My Kitchen Table by Molly Wizenberg (2009): Wizenberg reflects on the death of her father Burg from cancer, time spent living in Paris, building a new life in Seattle, starting her food blog, and meeting her husband through it. Each brief autobiographical essay is perfectly formed and followed by a relevant recipe, capturing precisely how food is tied up with memories.
Comfort Me with Apples: More Adventures at the Table by Ruth Reichl (2001): Reichl traces the rise of American foodie culture in the 1970s–80s (Alice Waters and Wolfgang Puck) through her time as a food critic for the Los Angeles Times, also weaving in personal history – from a Berkeley co-op with her first husband to a home in the California hills with her second after affairs and a sticky divorce. Throughout she describes meals in mouth-watering detail, like this Thai dish: “The hot-pink soup was dotted with lacy green leaves of cilantro, like little bursts of breeze behind the heat. … I took another spoonful of soup and tasted citrus, as if lemons had once gone gliding through and left their ghosts behind.”
Nature Books
Meadowland: The Private Life of an English Field by John Lewis-Stempel (2014): Lewis-Stempel is a proper third-generation Herefordshire farmer, but also a naturalist with a poet’s eye. Magical moments and lovely prose, as in “The dew, trapped in the webs of countless money spiders, has skeined the entire field in tiny silken pocket squares, gnomes’ handkerchiefs dropped in the sward.”
Landmarks by Robert Macfarlane: This new classic of nature writing zeroes in on the language we use to talk about our environment, both individual words – which Macfarlane celebrates in nine mini-glossaries alternating with the prose chapters – and the narratives we build around places, via discussions of the work of nature writers he admires. Whether poetic (“heavengravel,” Gerard Manley Hopkins’s term for hailstones), local and folksy (“wonty-tump,” a Herefordshire word for a molehill), or onomatopoeic (on Exmoor, “zwer” is the sound of partridges taking off), his vocabulary words are a treasure trove.
Theology Books
Amazing Grace: A Vocabulary of Faith by Kathleen Norris (1998): In few-page essays, Norris gives theological words and phrases a rich, jargon-free backstory through anecdote, scripture and lived philosophy. This makes the shortlist of books I would hand to skeptics to show them there might be something to this Christianity nonsense after all.
My Bright Abyss: Meditation of a Modern Believer by Christian Wiman (2013): Seven years into a cancer journey, Wiman, a poet, gives an intimate picture of faith and doubt as he has lived with them in the shadow of death. Nearly every page has a passage that cuts right to the quick of what it means to be human and in interaction with other people and the divine.
General Nonfiction
Penelope Fitzgerald: A Life by Hermione Lee (2013): Although Penelope Fitzgerald always guarded literary ambitions, she was not able to pursue her writing wholeheartedly until she had reared three children and nursed her hapless husband through his last illness. This is a thorough and sympathetic appreciation of an underrated author, and another marvellously detailed biography from Lee.
Being Mortal: Medicine and What Matters in the End by Atul Gawande (2014): A surgeon’s essential guide to decision-making about end-of-life care, but also a more philosophical treatment of the question of what makes life worth living: When should we extend life, and when should we concentrate more on the quality of our remaining days than their quantity? The title condition applies to all, so this is a book everyone should read.
Memoirs
The Year My Mother Came Back by Alice Eve Cohen: Wry and heartfelt, this is a wonderful memoir about motherhood in all its variations and complexities; the magic realism (Cohen’s dead mother keeps showing up) is an added delight. I recommend this no matter what sort of relationship, past or present, you have with your mother, especially if you’re also a fan of Anne Lamott and Abigail Thomas.
- The Art of Memoir
by Mary Karr: There is a wealth of practical advice here, on topics such as choosing the right carnal details (not sexual – or not only sexual – but physicality generally), correcting facts and misconceptions, figuring out a structure, and settling on your voice. Karr has been teaching (and writing) memoirs at Syracuse University for years now, so she’s thought deeply about what makes them work, and sets her theories out clearly for readers at any level of familiarity.
A Circle of Quiet by Madeleine L’Engle (1971): In this account of a summer spent at her family’s Connecticut farmhouse, L’Engle muses on theology, purpose, children’s education, the writing life, the difference between creating stories for children and adults, neighbors and fitting into a community, and much besides. If, like me, you only knew L’Engle through her Wrinkle in Time children’s series, this journal should come as a revelation.
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Do No Harm: Stories of Life, Death and Brain Surgery by Henry Marsh (2014): “Terrible job, neurosurgery. Don’t do it.” – luckily for us, Henry Marsh reports back from the frontlines of brain surgery so we don’t have to. In my favorite passages, Marsh reflects on the mind-blowing fact that the few pounds of tissue stored in our heads could be the site of our consciousness, our creativity, our personhood – everything we traditionally count as the soul.
I Hate to Leave This Beautiful Place by Howard Norman (2013): Norman has quickly become one of my favorite writers. You wouldn’t think these disparate autobiographical essays would fit together as a whole, given that they range in subject from Inuit folktales and birdwatching to a murder–suicide committed in Norman’s Washington, D.C. home and a girlfriend’s death in a plane crash, but somehow they do; after all, “A whole world of impudent detours, unbridled perplexities, degrading sorrow, and exacting joys can befall a person in a single season, not to mention a lifetime.”
Portrait of an Addict as a Young Man by Bill Clegg (2010): Through this book I followed literary agent Bill Clegg on dozens of taxi rides between generic hotel rooms and bar toilets and New York City offices and apartments; together we smoked innumerable crack pipes and guzzled dozens of bottles of vodka while letting partners and family members down and spiraling further down into paranoia and squalor. He achieves a perfect balance between his feelings at the time – being out of control and utterly enslaved to his next hit – and the hindsight that allows him to see what a pathetic figure he was becoming.
And my overall favorite nonfiction book of the year:
1. The Light of the World by Elizabeth Alexander: In short vignettes, beginning afresh with every chapter, Alexander conjures up the life she lived with – and after the sudden death of – her husband Ficre Ghebreyesus, an Eritrean chef and painter. This book is the most wonderful love letter you could imagine, and no less beautiful for its bittersweet nature.
What were some of your best nonfiction reads of the year?
Eleven-year-old Deming Guo and his mother Peilan (nicknamed “Polly”), an undocumented immigrant, live in New York City with another Fuzhounese family: Leon, Polly’s boyfriend, works in a slaughterhouse, and they share an apartment with his sister Vivian and her son Michael. Deming gets back from school one day to find that his mother never came home from her job at a nail salon. She’d been talking about moving to Florida to work in a restaurant, but how could she just leave him behind with no warning?
In Search of Mary
Italy Invades

Cultured Food for Health
40 Sonnets by Don Patterson: All but one of the poems in this new book have the sonnet’s traditional 14 lines; “The Version” is a short prose story about writing an untranslatable poem. However, even in the more conventional verses, there is a wide variety of both subject matter and rhyme scheme. Topics range from love and death to a phishing phone call and a footpath blocked off by Dundee City Council. A few favorites were “A Powercut,” set in a stuck elevator; “Seven Questions about the Journey,” an eerie call-and-response; and “Mercies,” a sweet elegy to an old dog put to sleep. There weren’t quite enough stand-outs here for my liking, but I appreciated the book as a showcase for just how divergent in form sonnets can be.
Without You There Is No Us by Suki Kim: This is a quietly gripping book even though not much of moment happens over Kim’s five months teaching young men at a missionary-run college in Pyongyang. She was in a unique position in that students saw her as ethnically one of their own but she brought an outsider’s perspective to bear on what she observed. Just before she flew back to the States in 2011, Kim Jong-Il died, an event she uses as a framing device. It could have represented a turning point for the country, but instead history has repeated itself with Kim Jong-un. Kim thus ends on a note of frustration: she wants better for these young men she became so fond of. A rare glimpse into a country that carefully safeguards its secrets and masks its truth.
Alive, Alive Oh!: And Other Things that Matter by Diana Athill: Diana Athill turns 98 on December 21st. Apart from “Dead Right,” however, this collection is not primarily concerned with imminent death. Instead Athill is still grateful to be alive: marveling at a lifetime of good luck and health and taking joy in gardening, clothing, books, memories and friendships. Six of the 10 essays originally appeared elsewhere. The collection highlight is the title piece, about a miscarriage she suffered in her forties. Another stand-out is “The Decision,” about moving into a retirement home in her nineties. This doesn’t live up to her best memoirs, but is an essential read for a devoted fan, and a consolation given she will likely not publish anything else (though you never know). [For first-time Athill readers, I’d recommend starting with 
My Confection
Good on Paper
The Secret Chord
When I Die
Twain’s End
Meadowland
A Homemade Life
The Ecco Book of Christmas Stories
The Tsar of Love and Techno
Mad Feast
Charlotte Brontë: A Life
Addiction Is Addiction
The Gratitude Diaries by Janice Kaplan: We can all do with a little encouragement to appreciate what we already have. In so many areas of life – finances, career, relationship, even the weather – we’re all too often hoping for more or better than what we are currently experiencing. Here Kaplan undertakes a year-long experiment to see if gratitude can improve every aspect of her life. She draws her information from interviews with researchers and celebrities, quotes from philosophers, and anecdotes from her own and friends’ lives. It’s easy, pleasant reading I’d recommend to fans of Gretchen Rubin.
The Water Book by Alok Jha: An interdisciplinary look at water’s remarkable properties and necessity for life on earth. For the most part, Jha pitches his work at an appropriate level. However, if it’s been a while since you studied chemistry at school, you may struggle. Part IV, on the search for water in space, is too in-depth for popular science and tediously long. In December 2013 Jha was part of a month-long Antarctic expedition. He uses the trip as an effective framing device, but I would have liked more memoiristic passages. All in all, I was hoping for less hard science and more reflection on water’s importance to human culture.
Claxton: Field Notes from a Small Planet by Mark Cocker: Mark Cocker is the Guardian’s country diarist for Norfolk. The short pieces in this book are reprints of his columns, some expanded or revised. I would advise keeping this as a bedside or coffee table book from which you read no more than one or two entries a week, so that you always stay in chronological sync. You’ll appreciate the book most if you experience nature along with Cocker, rather than reading from front cover to back in a few sittings. The problem with the latter approach is that there is inevitable repetition of topics across years. All told, after spending a vicarious year in Claxton, you’ll agree: “How miraculous that we are all here, now, in this one small place.”
A Mile Down by David Vann: Vann, better known for fiction, tells the real-life story of his ill-fated journeys at sea. He hired a Turkish crew to build him a boat of his own, and before long shoddy workmanship, language difficulties, bureaucracy, and debts started to make it all seem like a very bad idea. Was he cursed? Would he follow his father into suicide? The day-to-day details of boat-building and sailing can be tedious, and there’s an angry tone that’s unpleasant; Vann seems to think everybody else was incompetent or a crook. However, he does an incredible job of narrating two climactic storms he sailed through.
Running on the March Wind by Lenore Keeshig: Keeshig is a First Nations Canadian; these poems are full of images of Nanabush the Trickster, language from legal Indian acts, and sly subversion of stereotypes – cowboys and Indians, the only good Indian is a dead Indian (in “Making New”), the white man’s burden, and so on. In places I found these more repetitive and polemical than musical, though I did especially like the series of poems on trees.
Very British Problems Abroad
Purity
A Brief History of Seven Killings
Kitchens of the Great Midwest
The Japanese Lover
Accidental Saints: Finding God in All the Wrong People
The Road to Little Dribbling: Adventures of an American in Britain by Bill Bryson: Bryson’s funniest book for many years. It meant a lot to me since I am also an American expat in England. Two points of criticism, though: although he moves roughly from southeast to northwest in the country, the stops he makes are pretty arbitrary, and his subjects of mockery are often what you’d call easy targets. Do we really need Bryson’s lead to scorn litterbugs and reality television celebrities? Still, I released many an audible snort of laughter while reading.
Shaler’s Fish
Landfalls
Dept. of Speculation by Jenny Offill: Not as innovative or profound as I was expecting given the rapturous reviews from so many quarters. It’s an attempt to tell an old, old story in a new way: wife finds out her husband is cheating. Offill’s style is fragmentary and aphoristic. Some of the facts and sayings are interesting, but most just sit there on the page and don’t add to the story. What I did find worthwhile was tracing the several tense and pronoun changes: from first-person, past tense into present tense, then to third-person and back to first-person for the final page.
As Far As I Know by Roger McGough: A bit silly for my tastes; lots of puns and other plays on words. In style they feel like children’s poems, but with vocabulary and themes more suited to adults. I did like “Indefinite Definitions,” especially BRUPT: “A brupt is a person, curt and impolite / Brusque and impatient / Who thinks he’s always right.” The whole series is like that: words with the indefinite article cut off and an explanation playing on the original word’s connotations. From the “And So to Bed” concluding cycle, I loved Camp bed: “A la Recherche du Temps Perdu / on the bedside table / Gardenia on the pillow / Silk pyjamas neatly folded.”
The Penguin Lessons: What I Learned from a Remarkable Bird